Vol. 6, Issue 3 (2019)
Comparative efficacy of various anthelmintic drugs against Fascioliasis in cattle in Nangarhar, Afghanistan
Author(s): Redwanullah Memlawal, Ahmad Farid Rawan, Mohammad Hamid Kadwal
Abstract: The present study deals with the therapeutic trials against Fascioliasis. For this purpose a total of 80 cattle were used and were randomly divided into groups A1, A2, A3, B1, B2, B3, C and D. Efficacy of Fumaria parviflora aerial parts Centratherum anthelminticum and Triclabendazole against Fascioliasis were measured. Efficacy was quantified by determined the difference of eggs per gram of faeces pre and post treatment. Fumaria parviflora at a single dose of 50, 60 and 70 mg/kg body weight reduced EPG by 46.34, 53.65 and 59.52 percent respectively. After the second dose the reduction in EPG was 82.92, 90.24 and 92.85 percent respectively, Centratherum anthelminticum at a single dose of 50, 60 and 70 mg/kg body weight reduced EPG by 50.0, 53.48 and 56.09 percent respectively. After the second dose the respective reduction in EPG count was 71.42, 81.93 and 85.36 percent respectively, as Triclabendazole at recommended dose rate was 66.66 and 97.43 percent respectively effective at one and two dosage level. It was also noted that there was an increase in milk yield in all the treated groups. No side effects were reported in treated animals. The efficacy order of drugs was Triclabendazole, Fumaria parviflora and Centratherum anthelminticum.