International Journal of Multidisciplinary Research and Development

International Journal of Multidisciplinary Research and Development

E-ISSN: 2349-4182
P-ISSN: 2349-5979

Vol. 6, Issue 3 (2019)

Study of bacteriological profile and antibiotic resistance pattern of different organism isolated from pediatric and neonatal ICU at a Tertiary Care Hospital in Solapur Maharashtra

Author(s): Dr. Anu Sharma, Dr. NK Shaikh, Dr. DP Danave, Dr. Sonal Agarwal
Abstract: Introduction: Throughout the world multi-drug resistant nosocomial infections are one of the leading causes of deaths and morbidity amongst hospitalized patients. Microbiology reports supports in diagnosis and plays a vital role in determining the outcome and duration of the hospital stay for patients admitted in ICU. Regular surveillance of pathogens and its resistance pattern should be determined. Objectives: The aim of the study was to find out the bacteriological profile and antibiotic sensitivity pattern of organisms causing infection in patients admitted in Pediatric (PICU) and Neonatal ICU (NICU). Material & Method: Study was conducted from August 2018 to January 2019, total of 397 samples received in Microbiology from PICU & NICU. All samples were processed for culture and sensitivity, identification was done as per standard protocols and antibiotic susceptibility testing was done as per CLSI guidelines. Results: Out of 397 samples, 154(39.0%) samples were culture positive. The number of Gram-negative and Gram-positive organisms isolates were 118(76.12%) and 36 (23.22%) respectively. The most frequent Gram-negative organisms (n=118) isolated from PICU & NICU were Acinetobacter spp. 29(24.58%) followed by Klebsiella spp. 28 (18.06%), Pseudomonas aeruginosa 25 (21.2%), E.coli 21 (18%), Citrobacter koseri 5(4.23%). Among gram positive organisms (n=36) of Staphylococcus aureus were 30(83.33%) of which MRSA were 17 (47.22%), MRCONS were 10(28%) and MSSA were 3(8.33%). Enterococcus faecalis isolated were 6(16.66%). Antibiotic sensitivity pattern among gram negative isolates showed maximum resistance to Amikacin 85%, and least resistance was shown by Cotrimoxazole 32%. Among gram positive bacteria 100% sensitivity was seen for Vancomycin & Linezolid. Conclusion: Adherence of strict infection control measures, bundle care and regular antibiotic rotation should be followed in order to prevent antibiotic resistance.
Pages: 216-218  |  140 Views  36 Downloads
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