Vol. 2, Issue 8 (2015)
Relevance of thyroid dysfunction with age
Author(s): Shahnaz Attaullah, Bibi Safia Haq, Mairman Muska
Abstract: This study was conducted to evaluate the relevance of thyroid dysfunction in male & female subjects of different age groups. Thyroid dysfunction was diagnosed by the chemical analysis of thyroid function tests. A Total of 600 cases during the study period i.e. November 2011 to December 2012 were registered at the Institute of Radioactive Nuclear Medicine (IRNUM) Peshawar, Pakistan. The selected cases were analyzed for TSH, T4, and T3 by using Gamma counter. TSH in the sample is estimated by using Immuno Radiometric method (RIA). Primary data ingress was processed on MS Database version 2007. Data were checked in Epidemiological information (EPI-info), for scientific verifications. The data were finally imported in spread sheet statistical software (SPSS) version 20.0 for analysis. Patients of age group between 10-70 years were included. In this study most of the cases (30.8%) presenting with thyroid abnormalities are in the age group of 31-40 years, whereas only 0.3% were found in the age of 70 or more. Very few elderly were found having subclinical thyroid dysfunction (STD) in the age group of 41-60 and there is no evidence of the incidence of subclinical hypothyroidism (SCH-I) as well as subclinical hyperthyroidism (SCH-II) above 60 years of age. We report that on the basis of gender specification 4% of female subjects and 1% of male subjects were declared as SCH-I and SCH-II respectively. According to the results 36.6% of the total population in the age group 34-40 years were found to be having STD, out of which 10% are SCH-I and 26.6% are suffering from SCH-II. The ratio of male vs. female was 0:3(SCH-I) and 1:7 (SCH-II).