Vol. 2, Issue 5 (2015)
Correlation between fasting insulin and blood pressure in obese and non-obese middle aged Indian diabetic adults
Author(s): Raja Reddy P, Lakshmaiah V, Karthiyanee Kutty, Madhavi Reddy M, Munilakshmi U
Abstract: Objectives: To observe the relation between fasting insulin and blood pressure in obese and non-obese middle aged type two diabetes patients. Material and Methods: The present study was carried out at RL Jalappa Hospital attached to Sri Devaraj Urs Medical College, Tamaka, and Kolar. This study includes 276 diabetic patients with the age group of 40-50 years and WHO Body Mass Index Guidelines were used to classify the subjects into four groups. Anthropometric and biochemical measurements were evaluated by standard procedures. Statistical analysis was done by using SPSS version 16.0. Mean and standard deviation was done by ANOVA and Pearsonâ€™s correlation Coefficient was used to find association between various risk factors. Results: BMI was positively correlated with SBP and DBP values. The fasting insulin levels were also increased with BMI variations. Weight gain is associated with an increase in insulin resistance and this in turn leads to development of complications for diabetes includes cardiovascular and renal diseases. Obesity is a positive risk factor in the development of dyslipidemia, insulin resistance and hypertension, which are linked more strongly to intra-abdominal obesity. Conclusion: As the BMI increases fasting blood sugars and glycolated hemoglobin levels were decreased but fasting insulin levels were increased. However fasting insulin was positively correlated with blood pressure in obese subjects and negatively correlated with non-obese subjects.