oral submucosal fibrosis is common in betal nut and tobacco chewers in our region. Is this a premalignant condition or not, to find out this we took this study into consideration.rnAims and objectives: To study the etiopathology, symptomatology, clinicopathological findings of oral submucous fibrosis.rnTo study the stage of oral submucous fibrosis and its correlation with oral cancer.
Material and methods: This study consists of 50 random cases of oral submucous fibrosis attended general surgery and ENT OPD during 1 year period, in J.A. Group of Hospitals, Gwalior (M.P.).The patients were examined for any general disease and a detailed local examination was carried out.
Results: The salient features of the observations in the present study were as follows:-The maximum number of cases i.e. 22 (44%) were from the age group between 31-40 years.In sex distribution of OSF males were affected more than females in ratio of 4:1 which was similar to most of the previous studies. Religion wise, Hindu & Muslim communities were mostly affected. Burning senstation in mouth was the most common symptom. Other symptoms were trismus, ulceration, pain in throat & TM joint, anklyglossia, dysphasia and pain in ear. 16 cases were pan masala chewers which was the most common chewing habit in present study. Recently introduced pan masala has predilection for young age with causation of sub mucous fibrosis in short duration. Most of the patients present themselves for medical aid when disease was advanced (clinical state II). Anemia was found in 20 cases (40%) as shown by low hemoglobin percentage (<10gm) in those cases. Eosinophils were raised in 10 cases (20%). One case (2%) showed invasive squamous cell carcinoma of buccal cavity and one had cellular dysplasia. Clinical and histological correlation was done in all cases showing evidence of submucous fibrosis histologically. rn
Conclusion: Disease is probably a premalignant condition but needs further evaluation.rn