International Journal of Multidisciplinary Research and Development

International Journal of Multidisciplinary Research and Development

Online ISSN: 2349-4182
Print ISSN: 2349-5979

Vol. 2, Issue 10 (2015)

Cryotherapy in squamous intraepithelial lesions of cervix

Author(s): Pallavi Agarwal, Rajyashri Sharma, Ankur Varshney
Abstract: Aims: In this study we studied the safety, effectiveness and acceptability of Cryotherapy in cases with abnormal squamous intraepithelial lesions. rnMaterials and Methods: In our study, 60 patients in reproductive age group attending gynecology OPD, with complaints of discharge per vaginum, lower abdominal pain, and post coital bleeding were screened for HPV DNA by paper smear method. Also these patients were subjected to detailed history, per abdomen, per speculum and per vaginum examination, VIA and papanicolou smear. Colposcopy and biopsy was done in patients where indicated. Then cryotherapy was given to these patients and patients were followed up by same.rnResults: Cytological screening was done in 55 cases and it was found that 28(51%) were inflammatory, 15(27%) were LSIL, 2(8%) were AGUS, no ASCUS, 8(14%) were HSIL.VIA positive cases were 38 cases. On cytology they showe5% VIA negative were HPV positive and 95% cases were HPV negative. P-value is 0.038 which was statistically significant.d 17(45%) inflammatory, 13(34%) were LSIL, were 8(21%) were HSIL. pre-treatment 30(67%) cases had inflammatory smear, 11(24%) cases have LSIL cytology and 4(9%) case have HSIL. Post treatment none had LSIL& HSIL, 21(47%) converted to normal cytology and 24(53%) inflammatory smear. As the cases who had LSIL and AGUS initially after treatment turn normal or inflammatory. P value was 0.001, statistically significant. . 11 HPV positive cases were treated with cryotherapy and 8 cases turn negative showing P
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